Functional Magnetic Resonance Imaging (fMRI) is now a standard tool for mapping activation patterns in the human brain. This highly interdisciplinary field involves neuroscientists and physicists as well as clinicians, and the range, flexibility and sophistication of the techniques being used are increasing rapidly. In this book, Richard Buxton, a leading authority on fMRI, pro...
Functional Magnetic Resonance Imaging (fMRI) is now a standard tool for mapping activation patterns in the human brain. This highly interdisciplinary field involves neuroscientists and physicists as well as clinicians, and the range, flexibility and sophistication of the techniques being used are increasing rapidly. In this book, Richard Buxton, a leading authority on fMRI, provides an invaluable introduction to how fMRI works, from basic principles and the underlying physics and physiology, to newer techniques such as arterial spin labeling and diffusion tensor imaging. The book also includes discussion of how fMRI relates to other imaging techniques (such as Positron Emission Tomography, or PET) and a guide to the statistical analysis of fMRI data. This book will be useful both to the experienced researcher using fMRI, and the clinician or researcher with no previous knowledge of the technology.
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It was the discovery of the BOLD effect that significanty bradened the field of functional neuroimaging. Virtually all the fMRI performed to map patterns of brain activation are based on the BOLD effect. However , the BOLD effect has an important drawback for clinical applications: all that can be measured is a change in the perfusion state. That is, BOLD studies tell us nothing about the resting perfusion, only which areas change when the subject performs a different task. For clinical applications such as strock, the important measurement is the resting CBF, and so for this reason clinical fMRI studies are likely to require ASL techniques. (查看原文)
还没人写过短评呢
还没人写过短评呢