读过 Ten Drugs
The best way to get a long-lasting blockbuster is to make sure that it doesn't cure anything. Neither of the two big sellers from Pfizer just mentioned cures the underlying condition. Both erectile dysfunction and joint disease are painful in different ways, but neither is life threatening. Viagra and Celebrex treat symptoms, not diseases. Quality of life drugs that treat symptoms can be prescribed endlessly. If a patient stops taking them, the symptoms return, so they make money endlessly. Given the high costs of drug development, it's easy to understand why drug makers want that kind of payoff. The need for profit excuse the kinds of drugs that are developed. It explains why drug makers are putting very little effort into finding desperately needed new antibiotics, and a lot of money into finding drugs that can treat the symptoms of aging. It's not that big pharma isn't looking for drugs that will save the lives of patients. They are, especially in cancer treatment. But they need blockbuster quality of life drugs like Viagra to fund the process, and, after all, saving lives isn't everything. More than any pill ever to be dispensed, Viagra has played the yearnings of American culture: eternal youth, sexual prowess, not to mention the longing for an easy fix, one essayist opined. It is the perfect drug for our time.
- Sex, Drugs and More Drugs
Drugs moved us from fearing the diseases of childhood to suffering the diseases of the old. That's attributed medicine in general, and to drugs in particular. These are technological tools capable of changing our culture, but when you think about them, drugs are even stranger than that. Today's Pharmaceuticals are high tech developed in cutting edge laboratories, after investments of tens of millions of dollars. But a kind of high tech so intimate, so personal, that they have to become part of you to do their work. You have to snort them, drink and ingest them, inject them, rub them into your skin, make them part of your body. They dissolve inside you, and race through your blood from muscle to heart, liver to brain. Only when they're absorbed, when they have melted into you, and melted with you, does their power unfold. Then they can attach and trigger, soothe and calm, destroy and protect, alter your consciousness, restore your health. They can Jack you up, or chill you out. They can addict you, and they can save your life.
- 50,000 Pills