What can we learn from the genomes of our closest evolutionary relatives?
Neanderthal Man tells the story of geneticist Svante Pääbo’s mission to answer this question, and recounts his ultimately successful efforts to genetically define what makes us different from our Neanderthal cousins. Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in...
What can we learn from the genomes of our closest evolutionary relatives?
Neanderthal Man tells the story of geneticist Svante Pääbo’s mission to answer this question, and recounts his ultimately successful efforts to genetically define what makes us different from our Neanderthal cousins. Beginning with the study of DNA in Egyptian mummies in the early 1980s and culminating in the sequencing of the Neanderthal genome in 2010, Neanderthal Man describes the events, intrigues, failures, and triumphs of these scientifically rich years through the lens of the pioneer and inventor of the field of ancient DNA.
We learn that Neanderthal genes offer a unique window into the lives of our hominin relatives and may hold the key to unlocking the mystery of why humans survived while Neanderthals went extinct. Drawing on genetic and fossil clues, Pääbo explores what is known about the origin of modern humans and their relationship to the Neanderthals and describes the fierce debate surrounding the nature of the two species’ interactions. His findings have not only redrawn our family tree, but recast the fundamentals of human history—the biological beginnings of fully modern Homo sapiens, the direct ancestors of all people alive today.
A riveting story about a visionary researcher and the nature of scientific inquiry, Neanderthal Man offers rich insight into the fundamental question of who we are.
Svante Pääbo is the founder of the field of ancient DNA. The director of the department of genetics at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Pääbo has been featured in the New York Times, Newsweek, National Geographic, and The Economist, as well as on NPR, PBS, and BBC. In 2009 Time named him one of the 100 Most Influential People in the World. Pääb...
Svante Pääbo is the founder of the field of ancient DNA. The director of the department of genetics at the Max Planck Institute for Evolutionary Anthropology in Leipzig, Pääbo has been featured in the New York Times, Newsweek, National Geographic, and The Economist, as well as on NPR, PBS, and BBC. In 2009 Time named him one of the 100 Most Influential People in the World. Pääbo lives in Leipzig, Germany.
我希望在《自然》上发表的论文能激起足够的关注,从而让我获得更多来自民主德国的木乃伊样品,以便得到更多克隆并寻找有趣的基因,而非寻常的 Alu 序列。所以在《自然》发表论文几个月后,当罗斯季斯拉夫去东柏林为我安排再次采集木乃伊样品时,我以为会一帆风顺。不过他带回的消息令人不安。博物馆里的朋友都没有时间接待他,事实上,他们似乎都在故意避开他。最后,凑准某个家伙离开博物馆的时机,他将其堵在墙角质问。原来,《自然》刊登我的论文之后,民主德国秘密警察斯塔西(Stasi)出现在博物馆。他们在小房间里轮流审讯每个接待过我的工作人员,审问他们与我和罗斯季斯拉夫做了什么。因为引起了国家安全部门的注意,稍有常识的民主德国公民都不会再想和我们有任何瓜葛。 (查看原文)
发出来随缘吧,鬼知道。 这本书比起“科普作品”更多是作者自传和工作札记,缺少了这些八卦很是逊色。这让我想起如果Criag Packer的Lions in the Balance如果到国内出版会变成什么糟糕的样子(当然,我并不认为这本书会在国内出版) 帕波的生活过得有声有色,吃个饭爬个山出个...
(展开)
0 有用 国家特级壮女 2019-01-08 11:44:43
实在是太精彩了,有爱情有友情有争分夺秒也有苦苦找寻却停滞不前,把复杂的问题讲明白需要真正的学识,把一点一滴脚踏实地的日常研究讲有趣需要一颗赤子之心,2019年的开篇就看到这样一本从各个维度都给人提升的书真是幸福的事情,好莱坞为啥还不把它拍成电影,简直就是科学界的寻宝大片!
0 有用 mendel 2020-01-08 02:08:42
补标。大胆的自传,看过之后再次觉得天才的人生总会有些无需解释的奇葩点……本科时上顾博的进化课最早听到尼人基因组测序的故事,而且印象挺深那篇文章出人意料地发在了Cell上,时隔多年从这本书里重温细节。另外当时课上还提到张昀老师从恐龙蛋里克隆到基因片段,投稿被拒的故事,当时只听一面之辞觉得很不公平很可惜,读完本书的某章节也有了更客观的认识。