出版社: John Wiley & Sons, Ltd
副标题: Fifth Edition
出版年: 2015-9
页数: 151
装帧: Paperback
ISBN: 9781118997772
内容简介 · · · · · ·
How the Immune System Works has helped thousands of students understand what’s in their big, thick, immunology textbooks. In his book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject.
In fifteen easy-to-read chapters, featuring the humorous style and engaging analogies developed by Dr. Sompayrac, How the Immun...
How the Immune System Works has helped thousands of students understand what’s in their big, thick, immunology textbooks. In his book, Dr. Sompayrac cuts through the jargon and details to reveal, in simple language, the essence of this complex subject.
In fifteen easy-to-read chapters, featuring the humorous style and engaging analogies developed by Dr. Sompayrac, How the Immune System Works explains how the immune system players work together to protect us from disease – and, most importantly, why they do it this way.
Rigorously updated for this fifth edition, How the Immune System Works includes the latest information on subjects such as vaccines, the immunology of AIDS, and cancer. A highlight of this edition is a new chapter on the intestinal immune system – currently one of the hottest topics in immunology.
Whether you are completely new to immunology, or require a refresher, How the Immune System Works will provide you with a clear and engaging overview of this fascinating subject. But don’t take our word for it! Read what students have been saying about this classic book:
"What an exceptional book! It's clear you are in the hands of an expert."
"Possibly the Best Small Text of All Time!"
http://as.wiley.com/WileyCDA/WileyTitle/productCd-EHEP003432.html
目录 · · · · · ·
Acknowledgments, vii
How to Use This Book, viii
This book is neither a comprehensive text nor an exam-review tool. It is an overview of the immune system, designed to give anyone who is learning immunology a feel for how the system fits together.
Lecture 1 An Overview, 1
The immune system is a “team effort,” involving many different players who work together to provide a powerful defense against invaders. Focusing in on one player at a time makes it hard to understand the game. Here we view the action from the grandstands to get a wide-angle picture of what the immune system is all about.
· · · · · · (更多)
Acknowledgments, vii
How to Use This Book, viii
This book is neither a comprehensive text nor an exam-review tool. It is an overview of the immune system, designed to give anyone who is learning immunology a feel for how the system fits together.
Lecture 1 An Overview, 1
The immune system is a “team effort,” involving many different players who work together to provide a powerful defense against invaders. Focusing in on one player at a time makes it hard to understand the game. Here we view the action from the grandstands to get a wide-angle picture of what the immune system is all about.
Lecture 2 The Innate Immune System, 13
The innate immune system is a “hard-wired” defense that has evolved over millions of years to recognize pathogens that commonly infect humans. It provides a rapid and powerful response against “everyday” invaders.
Lecture 3 B Cells and Antibodies, 27
B cells and the antibodies they produce are part of the adaptive immune system. This defense evolves during our own lifetime to protect us against invaders that we, personally, have never encountered before.
Lecture 4 The Magic of Antigen Presentation, 42
T cells, another weapon of the adaptive immune system, only recognize invaders which are “properly presented” by specialized antigen presenting cells. This feature keeps these important cells focused on the particular attackers which they are able to defend against.
Lecture 5 T Cell Activation, 55
Before they can spring into action, T cells must be activated. This requirement helps insure that only useful weapons will be mobilized.
Lecture 6 T Cells at Work, 63
Once they have been activated, helper T cells orchestrate the immune response, and killer T cells destroy infected cells.
Lecture 7 Secondary Lymphoid Organs and Lymphocyte Trafficking, 72
B and T lymphocytes travel through secondary lymphoid organs looking for the intruders they can defend against. Once activated in the secondary lymphoid organs, B and T cells are dispatched to the particular areas of the body where they can be most useful.
Lecture 8 Restraining the Immune System, 84
The powerful weapons of the immune system must be restrained lest they become overexuberant. In addition, once an invader has been defeated, the immune system must be “reset” to prepare for future attacks.
Lecture 9 Self Tolerance and MHC Restriction, 88
T cells must be trained to focus on appropriately presented invaders, and B and T lymphocytes must learn not to attack our own bodies.
Lecture 10 Immunological Memory, 98
The innate immune system remembers pathogens which have been attacking humans for millions of years. In contrast, B and T cells remember pathogens we have encountered during our lifetime. Memory B and T lymphocytes respond more quickly and effectively to a subsequent attack by the same invader.
Lecture 11 The Intestinal Immune System, 103
The human intestines are home to trillions of bacteria, viruses, fungi, and parasites. How the immune system deals with these potentially dangerous intestinal residents, which frequently invade the tissues surrounding the intestines, is a hot topic in immunology.
Lecture 12 Vaccines, 110
Vaccines safely mimic the attack of an invader so that our immune system will be primed and ready for a future challenge by the same invader.
Lecture 13 The Immune System Gone Wrong, 116
The immune system generally does a good job of defending us without causing a lot of “collateral damage.” Sometimes, however, mistakes are made.
Lecture 14 Immunodeficiency, 126
Serious disease may result when our immune system does not operate at full strength. Humans who are infected with the AIDS virus have profoundly impaired immune systems.
Lecture 15 Cancer and the Immune System, 131
The human immune system is not very good at defending us against cancer. Indeed, there is a built-in conflict between the need to minimize the chance that its weapons will attack our own bodies, and the need to destroy wannabe cancer cells.
Glossary, 139
Here are definitions of some of the terms that immunologists use – but which “normal” people wouldn’t.
List of Acronyms and Abbreviations, 142
Immunologists are big on acronyms and abbreviations, so I’ve made a list to which you can refer.
Index, 143
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How the Immune System Works, 5th Edition的书评 · · · · · · ( 全部 6 条 )
免疫原来可以这样学~
免疫学难学是公认的,而此书作者却能深入浅出,于浅显易懂故事中讲出复杂的学术理论,真正好的科普书。国内教材偏于古板,把艰深的理论配上古板的讲述很难不让人觉得难学。期待国内的大咖能多做一些这样的科普。
看过之后,才知道啥是大道至简
> 更多书评 6篇
论坛 · · · · · ·
在这本书的论坛里发言这本书的其他版本 · · · · · · ( 全部9 )
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Wiley Blackwell9.9分 26人读过
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北京大学医学出版社 (2016)9.6分 103人读过
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Blackwell Pub暂无评分 12人读过
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订阅关于How the Immune System Works, 5th Edition的评论:
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4 有用 丁丁虫 2018-09-02 16:24:30
我现在觉得看这种原版课本比看小说更好,语句通俗易懂,只要搞定若干术语,基本上就没什么阅读障碍,还能学到各种知识
2 有用 之龢 2018-11-07 23:36:03
The first book, touched me, about medicine. From cluelessness, knowledge’s made through hypothesizes, tests, on animals and humans, and repeated failures with pain and wait. It’s humorously written, w... The first book, touched me, about medicine. From cluelessness, knowledge’s made through hypothesizes, tests, on animals and humans, and repeated failures with pain and wait. It’s humorously written, with respects to ‘Mother Nature.’ We learn how we were made, and cope with it. In the end, we’re Created, like other animals. (展开)
1 有用 jimmy198360 2019-03-09 05:00:57
免疫学入门必读神作。
0 有用 厚朴 2022-01-11 22:49:21
amazing!sehr klug und Wunderbar!
0 有用 阿喜 2022-06-07 18:04:50
对新手非常友好,简明扼要地把整体框架拎出来理清楚了,作者功力还是很牛的。看得过程也非常愉快,各种比喻小结,方便理解和记忆。之前看Janeway's Immunobiology头皮发麻,觉得自己不适合学免疫,幸好碰到这本书给自己了一点信心。强烈推荐这本书给免疫小白入门!
0 有用 🙊 2023-12-01 21:12:13 湖南
竟然还有如此好读的教材!
0 有用 阿喜 2022-06-07 18:04:50
对新手非常友好,简明扼要地把整体框架拎出来理清楚了,作者功力还是很牛的。看得过程也非常愉快,各种比喻小结,方便理解和记忆。之前看Janeway's Immunobiology头皮发麻,觉得自己不适合学免疫,幸好碰到这本书给自己了一点信心。强烈推荐这本书给免疫小白入门!
0 有用 厚朴 2022-01-11 22:49:21
amazing!sehr klug und Wunderbar!
0 有用 Weilin 2021-07-21 16:43:05
最近被导师推荐了这样一本书,因为之前学过免疫学,这本书非常的通俗易懂而且每一个章节短小精悍,对于难懂的概念用幽默的类比和例子也解释的非常详细。非常适合初学者。建议1-10章一口气看完,再看11-15章。
0 有用 shingeki 2020-04-20 16:19:05
当作免疫科普囫囵吞枣看了一遍,虽然名词概念挺多的但行文生动很多可爱的比喻,大部分还比较好理解,感叹下免疫系统又庞杂又微妙有种光明和黑暗随时可以转变的感觉。 天然免疫简单又快又猛,巨噬细胞很全能但被欺骗了也很致命,适应性免疫针对性强激发比较慢还有各种条件制约(t, b细胞各种类型很多阶段好复杂)~ 印象最深的是免疫系统倾向于包容自身的抗原,造成对很多细胞癌变没有足够的警觉~