作者:
Matt Richtel 出版社: William Morrow 副标题: The Extraordinary New Science of the Immune System: A Tale in Four Lives 出版年: 2019-3-12 页数: 448 装帧: Hardcover ISBN: 9780062698537
Magnificently reported and soulfully crafted, An Elegant Defense is an epic, first-of-its-kind exploration of the human immune system and the secrets of health, by the Pulitzer Prize–winning New York Times journalist“One of those rare nonfiction books that transcends the genre. ... Fascinating and engrossing. ... I highly recommend this extraordinary book.” —DOUGLAS PRESTON“Viv...
Magnificently reported and soulfully crafted, An Elegant Defense is an epic, first-of-its-kind exploration of the human immune system and the secrets of health, by the Pulitzer Prize–winning New York Times journalist“One of those rare nonfiction books that transcends the genre. ... Fascinating and engrossing. ... I highly recommend this extraordinary book.” —DOUGLAS PRESTON“Vividly told. ... Explicates for the lay reader the intricate biology of our immune system." —JEROME GROOPMAN, New York Review of BooksA terminal cancer patient rises from the grave. A medical marvel defies HIV. Two women with autoimmunity discover their own bodies have turned against them. Matt Richtel's An Elegant Defense uniquely entwines these intimate stories with science’s centuries-long quest to unlock the mysteries of sickness and health, and illuminates the immune system as never before.The immune system is our body’s essential defense network, a guardian vigilantly fighting illness, healing wounds, maintaining order and balance, and keeping us alive. Its legion of microscopic foot soldiers—from T cells to “natural killers”—patrols our body, linked by a nearly instantaneous communications grid. It has been honed by evolution over millennia to face an almost infinite array of threats. For all its astonishing complexity, however, the immune system can be easily compromised by fatigue, stress, toxins, advanced age, and poor nutrition—hallmarks of modern life—and even by excessive hygiene. Paradoxically, it is a fragile wonder weapon that can turn on our own bodies with startling results, leading today to epidemic levels of autoimmune disorders. Richtel effortlessly guides readers on a scientific detective tale winding from the Black Plague to twentieth-century breakthroughs in vaccination and antibiotics, to the cutting-edge laboratories that are revolutionizing immunology—perhaps the most extraordinary and consequential medical story of our time. The foundation that Richtel builds makes accessible revelations about cancer immunotherapy, the microbiome, and autoimmune treatments that are changing millions of lives. An Elegant Defense also captures in vivid detail how these powerful therapies, along with our behavior and environment, interact with the immune system, often for the good but always on a razor’s edge that can throw this remarkable system out of balance.Drawing on his groundbreaking reporting for the New York Times and based on extensive new interviews with dozens of world-renowned scientists, Matt Richtel has produced a landmark book, equally an investigation into the deepest riddles of survival and a profoundly human tale that is movingly brought to life through the eyes of his four main characters, each of whom illuminates an essential facet of our “elegant defense.”
作者简介
· · · · · ·
Matt Richtel is a Pulitzer Prize-winning New York Times journalist and bestselling writer of mysteries and thrillers. His books are fast-paced, character-centered stories in which things are not always as they seem. The backdrop for the books is the modern world. Technology is everywhere. Everything moves at lightning speed, from conspiracy, to love, business, and violence. Tec...
Matt Richtel is a Pulitzer Prize-winning New York Times journalist and bestselling writer of mysteries and thrillers. His books are fast-paced, character-centered stories in which things are not always as they seem. The backdrop for the books is the modern world. Technology is everywhere. Everything moves at lightning speed, from conspiracy, to love, business, and violence. Technology is our slave. Or has it become our dark master?
The books relate to Matt's journalism. He won the Pulitzer Prize in 2010 for a series of stories on distracted driving. The next year, he wrote an acclaimed series for the New York Times called "Your Brain On Computers" exploring how heavy technology use impacts our behavior and our brains.
Matt lives with his family in San Francisco. He writes from an office with a window that looks onto the former house of baseball legend Willie Mays. He -- Matt, not Willie -- is an avid tennis player, takes pride in making guacamole and coffee, and writes the occasional song.
1 有用 Shifumi 2020-02-21 14:56:29
虽然读这本书是因为受疫情的影响,但是觉得自己能够找到这本书作为通往医学知识的敲门砖实在是太幸运了。人类的身体是另一个雄伟而瑰丽的宇宙,感谢作者用简洁的语言向我们诉说了这一切。最令我惊讶的是某些我认为要靠大脑思考得出的哲学理论早就藏在了身体里,比如有伤口才会催发分裂,然后分裂过程中的突变又为人带来的癌症的风险。又比如免疫系统不能太强,否则就像管制严格的警察,会令无辜的人受害。这些在我们身体的奥秘,和... 虽然读这本书是因为受疫情的影响,但是觉得自己能够找到这本书作为通往医学知识的敲门砖实在是太幸运了。人类的身体是另一个雄伟而瑰丽的宇宙,感谢作者用简洁的语言向我们诉说了这一切。最令我惊讶的是某些我认为要靠大脑思考得出的哲学理论早就藏在了身体里,比如有伤口才会催发分裂,然后分裂过程中的突变又为人带来的癌症的风险。又比如免疫系统不能太强,否则就像管制严格的警察,会令无辜的人受害。这些在我们身体的奥秘,和今日社会中运行的法则何其相似。当然,最简单朴实的道理莫过于:睡好觉,吃好饭,懂得纾解压力。因为作者引用了一些朋友的病例,读的时候几次想为他的感性落泪。但是不得不承认,恰恰是他的认真记录保持了本书的真实性。好读,真的好好读哦。 (展开)
0 有用 Soo Yung 2019-10-16 03:29:02
A boring story of the immune system. Too scattered. SY 9/22
0 有用 无善无恶 2020-01-30 20:40:18
大多数人认为免疫系统就是攻击和防卫。防卫,是的,攻击就未必。免疫系统一直保持平衡,攻击最必要的,还必须与包围它,入侵它的生物体互相合作,它的核心工作是:将异类隔绝于自我之外,要做到这件事,就不能只做摧毁异类的事。 冲突必然会发生,免疫系统有时必须扮演强悍的防卫角色。但是免疫系统提醒我们,要尽可能采取破坏性最小的途径以达到可接受的平衡。当我们不合作,我们都会极力仿效我们特征中最具自我毁灭的一种:防卫... 大多数人认为免疫系统就是攻击和防卫。防卫,是的,攻击就未必。免疫系统一直保持平衡,攻击最必要的,还必须与包围它,入侵它的生物体互相合作,它的核心工作是:将异类隔绝于自我之外,要做到这件事,就不能只做摧毁异类的事。 冲突必然会发生,免疫系统有时必须扮演强悍的防卫角色。但是免疫系统提醒我们,要尽可能采取破坏性最小的途径以达到可接受的平衡。当我们不合作,我们都会极力仿效我们特征中最具自我毁灭的一种:防卫过度。拥有超强的免疫系统是最大的误解。 无处不在的“增强免疫力!”-大错特错。 (展开)
0 有用 豆友183248999 2023-02-26 15:46:49 上海
399
0 有用 豆友183248999 2023-02-26 15:46:49 上海
399
1 有用 Shifumi 2020-02-21 14:56:29
虽然读这本书是因为受疫情的影响,但是觉得自己能够找到这本书作为通往医学知识的敲门砖实在是太幸运了。人类的身体是另一个雄伟而瑰丽的宇宙,感谢作者用简洁的语言向我们诉说了这一切。最令我惊讶的是某些我认为要靠大脑思考得出的哲学理论早就藏在了身体里,比如有伤口才会催发分裂,然后分裂过程中的突变又为人带来的癌症的风险。又比如免疫系统不能太强,否则就像管制严格的警察,会令无辜的人受害。这些在我们身体的奥秘,和... 虽然读这本书是因为受疫情的影响,但是觉得自己能够找到这本书作为通往医学知识的敲门砖实在是太幸运了。人类的身体是另一个雄伟而瑰丽的宇宙,感谢作者用简洁的语言向我们诉说了这一切。最令我惊讶的是某些我认为要靠大脑思考得出的哲学理论早就藏在了身体里,比如有伤口才会催发分裂,然后分裂过程中的突变又为人带来的癌症的风险。又比如免疫系统不能太强,否则就像管制严格的警察,会令无辜的人受害。这些在我们身体的奥秘,和今日社会中运行的法则何其相似。当然,最简单朴实的道理莫过于:睡好觉,吃好饭,懂得纾解压力。因为作者引用了一些朋友的病例,读的时候几次想为他的感性落泪。但是不得不承认,恰恰是他的认真记录保持了本书的真实性。好读,真的好好读哦。 (展开)
0 有用 无善无恶 2020-01-30 20:40:18
大多数人认为免疫系统就是攻击和防卫。防卫,是的,攻击就未必。免疫系统一直保持平衡,攻击最必要的,还必须与包围它,入侵它的生物体互相合作,它的核心工作是:将异类隔绝于自我之外,要做到这件事,就不能只做摧毁异类的事。 冲突必然会发生,免疫系统有时必须扮演强悍的防卫角色。但是免疫系统提醒我们,要尽可能采取破坏性最小的途径以达到可接受的平衡。当我们不合作,我们都会极力仿效我们特征中最具自我毁灭的一种:防卫... 大多数人认为免疫系统就是攻击和防卫。防卫,是的,攻击就未必。免疫系统一直保持平衡,攻击最必要的,还必须与包围它,入侵它的生物体互相合作,它的核心工作是:将异类隔绝于自我之外,要做到这件事,就不能只做摧毁异类的事。 冲突必然会发生,免疫系统有时必须扮演强悍的防卫角色。但是免疫系统提醒我们,要尽可能采取破坏性最小的途径以达到可接受的平衡。当我们不合作,我们都会极力仿效我们特征中最具自我毁灭的一种:防卫过度。拥有超强的免疫系统是最大的误解。 无处不在的“增强免疫力!”-大错特错。 (展开)
0 有用 Soo Yung 2019-10-16 03:29:02
A boring story of the immune system. Too scattered. SY 9/22