作者:
David A. Sinclair
/
Matthew D. LaPlante 出版社: Atria Books 副标题: Why We Age—and Why We Don't Have To 出版年: 2019-9-10 页数: 432 定价: USD 14.99 装帧: 平装 ISBN: 9781501191978
From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting book shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls readers to consider a future where aging can be treated. For decades, experts have believed that we are at th...
From an acclaimed Harvard professor and one of Time’s most influential people, this paradigm-shifting book shows how almost everything we think we know about aging is wrong, offers a front-row seat to the amazing global effort to slow, stop, and reverse aging, and calls readers to consider a future where aging can be treated. For decades, experts have believed that we are at the mercy of our genes, and that natural damage to our genes—the kind that inevitably happens as we get older—makes us become sick and grow old. But what if everything you think you know about aging is wrong? What if aging is a disease—and that disease is treatable? In Lifespan, one of the world’s foremost experts on aging and genetics reveals a groundbreaking new theory that will forever change the way we think about why we age and what we can do about it. Aging isn’t immutable; we can have far more control over it than we realize. This eye-opening and provocative work takes us to the frontlines of research that is pushing the boundaries on our perceived scientific limitations, revealing incredible breakthroughs—many from Dr. David Sinclair’s own lab—that demonstrate how we can slow down, or even reverse, the genetic clock. The key is activating newly discovered vitality genes—the decedents of an ancient survival circuit that is both the cause of aging and the key to reversing it. Dr. Sinclair shares the emerging technologies and simple lifestyle changes—such as intermittent fasting, cold exposure, and exercising with the right intensity—that have been shown to help lead to longer lives. Lifespan provides a roadmap for taking charge of our own health destiny and a bold new vision for the future when humankind is able to live to be 100 years young.
作者简介
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David Sinclair, PhD, AO is a professor of genetics at Harvard Medical School. One of the leading innovators of his generation, he has been named by Time as “one of the 100 most influential people in the world” and top 50 most influential people in healthcare. He is a board member of the American Federation for Aging Research and has received more than 35 awards for his research...
David Sinclair, PhD, AO is a professor of genetics at Harvard Medical School. One of the leading innovators of his generation, he has been named by Time as “one of the 100 most influential people in the world” and top 50 most influential people in healthcare. He is a board member of the American Federation for Aging Research and has received more than 35 awards for his research and major scientific breakthroughs. Dr. Sinclair and his work have been featured on 60 Minutes, Today, The Wall Street Journal, The New York Times, Fortune, and Newsweek, among others. He lives in Boston and enjoys hiking and kayaking with his wife and three children. To learn more, visit LifespanBook.com and follow him on Twitter @DavidASinclair.
Matthew LaPlante is an associate professor of journalistic writing at Utah State University, where he teaches news reporting and feature writing. A former US Navy intelligence specialist and Middle East war correspondent, he is the author of Superlative: The Biology of Extremes and the cowriter of multiple other books on the intersection of science and society. He lives in Salt Lake City and skis in Big Cottonwood Canyon. To learn more, visit MDLaPlante.com and follow him on Twitter @MDLaPlante.
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目录
· · · · · ·
Introduction: A Grandmother’s Prayer
PART I: WHAT WE KNOW (THE PAST)
1. Viva Primordium
2. The Demented Pianist
3. The Blind Epidemic
PART II: WHAT WE’RE LEARNING (THE PRESENT)
· · · · · ·
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Introduction: A Grandmother’s Prayer
PART I: WHAT WE KNOW (THE PAST)
1. Viva Primordium
2. The Demented Pianist
3. The Blind Epidemic
PART II: WHAT WE’RE LEARNING (THE PRESENT)
4. Longevity Now
5. A Better Pill to Swallow
6. Big Steps Ahead
7. The Age of Innovation
PART III: WHERE WE’RE GOING (THE FUTURE)
8. The Shape of Things to Come
9. A Path Forward
Conclusion
Acknowledgement
Notes
Sinclair Disclosure
The Scale of Things
Cast of Characters
Glossary
Index
· · · · · · (收起)
At the nanoscale, it is merely an ordered set of chemical reactions, concentrating and assembling atoms that would normally never assemble, or breaking apart molecules that would normally never disintegrate. Life does this using proteinaceous Pac-Men called enzymes made up of coils and layered mats of amino acid chains.
Enzymes make life possible by taking advantage of fortuitous molecular movements. Every second you are alive, thousands of glucose molecules are captured within each of your trillion of cells by an enzyme called glucokinase, which fuse glucose molecules to phosphorus atoms, tagging them for energy production. Most of the energy created is used by a multicomponent RNA and protein complex called a ribosome, whose primary job is to capture amino acids and fuse them with other... (查看原文)
fasting,定期禁食一下下;运动,特别是 High Intensity Interval Training (HIIT),和 diet 甚至 fasting 结合;时不时让自己受冻一下,也是不是让自己热一下(比如蒸桑拿)。总之就是时不时让自己有点危机感,多激活一下体内在远古时代还是单细胞的时候就进化出来的遗传信息自检、查错和修复机制。
“ Aging is a disease.” Anti-aging is more about extending healthspan than it is about lengthening lifespan. It’s really eye-opening to read David Sinclair’ s Lifespan, which is about the root cause of aging and how to increase longevity and prolong vita...
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9 有用 GW_Parables 2020-04-30 22:04:52
大学同学因为个人原因天天来我家吃3顿饭 不好意思白吃 送了我一些书..这书一看就是瞎拼凑的..作者是NMN教主啊..还让绝经妇女重新例假的神棍..还很厚脸皮说自己40岁就放弃了甜品..我心想..都吃了40年了的sweets你抗衰老?还神神叨叨列举了自己的regimen心得..说他本人和家人和实验室的做法都是如此..inform下读者..看到笑死..本韭菜打小就那样做的啊..都是基于常识的选择..作... 大学同学因为个人原因天天来我家吃3顿饭 不好意思白吃 送了我一些书..这书一看就是瞎拼凑的..作者是NMN教主啊..还让绝经妇女重新例假的神棍..还很厚脸皮说自己40岁就放弃了甜品..我心想..都吃了40年了的sweets你抗衰老?还神神叨叨列举了自己的regimen心得..说他本人和家人和实验室的做法都是如此..inform下读者..看到笑死..本韭菜打小就那样做的啊..都是基于常识的选择..作者是哈佛教授..Harvard community有N多机构..HMS我目测就有好几个医院和研究机构 各色人员繁杂往来..顶个贵佛的锅出的这种让人捧腹的书.. (展开)
0 有用 WOO 2023-11-01 08:02:14 上海
激活人类原始的生存回路 ,少吃 保持饥饿 ,5/2 IF,每天 10 分钟HIIT ,寒冷 chill
0 有用 MX 2024-02-03 23:56:23 日本
Can we stop allowing sloppy writing to be published thx.
0 有用 Dorothy 2022-11-15 00:05:36 广东
Mind-blowing masterpiece!!
4 有用 青豆 2021-12-01 08:02:06
fasting,定期禁食一下下;运动,特别是 High Intensity Interval Training (HIIT),和 diet 甚至 fasting 结合;时不时让自己受冻一下,也是不是让自己热一下(比如蒸桑拿)。总之就是时不时让自己有点危机感,多激活一下体内在远古时代还是单细胞的时候就进化出来的遗传信息自检、查错和修复机制。